Biostimulators • Health Canada Compliant
Revive. Restore. Rebuild — The Natural Way
Turn back time with your body’s own collagen. Long-lasting results, subtle transformation, and glowing confidence — no overfilled look, no downtime.
Why clients choose this
Top 3 Benefits of Biostimulator Procedures
Natural Collagen Regeneration
Stimulates the body’s own collagen production for longer-lasting results.
Gradual, Natural-Looking Results
Avoids the “overdone” look common with some fillers.
Long-Lasting Youthfulness
Results often last 12–24 months, improving skin quality over time.
About the Treatment
What is a Biostimulator?
Biostimulators are advanced injectable treatments designed to stimulate your body’s natural collagen production, restoring firmness, volume, and elasticity to the skin. Unlike traditional dermal fillers, which add volume instantly, biostimulators work gradually, encouraging your body to rebuild its own structural support for a natural and youthful appearance. In aesthetic medicine, biostimulators are valued for their ability to improve skin texture, minimize wrinkles, and maintain results for years with proper care. They are ideal for those seeking subtle, yet transformative rejuvenation.
Safety First
Is Biostimulator Treatment Safe?
Yes. Biostimulators have undergone extensive clinical testing and have been safely used in aesthetic medicine for decades. When administered by a qualified physician, these treatments carry minimal risk. They are made from biocompatible materials that naturally integrate into your skin tissue and dissolve over time. As with any medical procedure, mild swelling, redness, or tenderness can occur temporarily. Choosing a licensed, experienced injector ensures optimal safety and results.
Value
Why is Biostimulator Treatment Important?
As we age, collagen production drops significantly, leading to sagging skin, fine lines, and volume loss. Biostimulators address the root cause by encouraging the skin to produce new collagen, restoring youthful structure and resilience. This makes them not only a corrective measure but also a preventative approach to aging.
You’re Not Just Aging—You’re Losing Collagen.
You’ve tried serums, facials, and injectables—yet your skin still looks tired, thin, or sagging. At Royal Glow by Meditism, we believe you deserve more than temporary fixes.
That’s where Biostimulators come in.
We help your skin rebuild itself from within—triggering natural collagen production, smoothing fine lines, restoring volume, and tightening skin over time.
Signature Menu
Discover the Art of Facial Balance with Dermal Fillers
Signature Menu
Are There Any Natural Biostimulators?
Platelet-Rich Plasma (PRP)
PRP is derived from your own blood and contains a high concentration of growth factors that stimulate collagen production, improve skin tone, and accelerate healing. After a small blood sample is taken, it is spun in a centrifuge to separate the platelet-rich layer. This is then injected or microneedled into the skin. Because it comes from your own body, PRP is completely biocompatible and carries no risk of allergic reaction. It is ideal for rejuvenating the face, neck, décolletage, and hands, as well as for improving skin texture and reducing fine lines.
Platelet-Rich Fibrin (PRF)
PRF is the next generation of PRP, created by spinning your blood at a lower speed to preserve more platelets, white blood cells, and stem cells within a fibrin matrix. This matrix slowly releases growth factors over time, allowing for longer-lasting collagen stimulation. PRF is particularly effective for under-eye rejuvenation, fine lines, and skin texture improvement. It’s also used in combination with other aesthetic treatments to speed healing and maximize results. Since it’s 100% natural and autologous, PRF is an excellent choice for patients seeking safe, chemical-free skin rejuvenation with long-term regenerative benefits.
Polynucleotides (PN) from Salmon DNA
Polynucleotides are naturally derived from purified salmon sperm DNA, which closely resembles human DNA, making it highly biocompatible. These long-chain molecules work to repair damaged skin cells, stimulate fibroblasts to produce collagen and elastin, and improve skin hydration. PN treatments are particularly popular in Asia and Europe for restoring skin elasticity, reducing fine lines, and speeding post-procedure healing. They also have antioxidant and anti-inflammatory properties, making them suitable for sensitive or aging skin. Known under brand names like Rejuran®, PN injections are an excellent natural biostimulator option for patients seeking both repair and rejuvenation.
Microneedling (Collagen Induction Therapy)
Microneedling is a minimally invasive treatment that uses fine needles to create tiny punctures in the skin. This controlled micro-injury process triggers the skin’s natural healing mechanisms, stimulating the production of new collagen and elastin. Over time, this leads to smoother texture, improved firmness, and reduced wrinkles or scars. Microneedling can be performed on the face, neck, décolletage, and hands, and is often combined with serums, PRP, or exosomes to enhance results. Because the collagen boost comes from your own body’s repair process, microneedling is a natural and safe method for skin rejuvenation.
Laser Skin Resurfacing
Laser skin resurfacing uses controlled light energy to create micro-injuries in the skin’s surface. This triggers the body’s natural wound-healing process, resulting in new collagen and elastin production. Certain lasers, like fractional CO₂ or erbium, not only smooth out fine lines and wrinkles but also improve pigmentation, scars, and overall texture. Although the device is man-made, the collagen-stimulating effect it produces is 100% natural because it’s driven by your body’s healing response. Recovery time varies depending on the depth of treatment, but the results can be transformative and long-lasting when paired with good skincare maintenance.
Vitamin C Collagen Therapy
Vitamin C is a powerful antioxidant and a crucial nutrient for collagen synthesis. In aesthetic treatments, high-concentration vitamin C is delivered topically, via microneedling, or in injectable form to directly stimulate fibroblasts and protect against oxidative damage. It helps brighten dull skin, fade pigmentation, and enhance firmness. By neutralizing free radicals, vitamin C also slows the breakdown of existing collagen, allowing results to last longer. This treatment is entirely natural, as it works with your body’s own biology to encourage healthier, more youthful-looking skin while offering strong protection against environmental stressors.
Exosome Therapy
Exosomes are tiny, cell-derived vesicles rich in growth factors, peptides, and signaling molecules. They are often sourced from stem cells and used to supercharge skin regeneration. When applied or injected, exosomes enhance cell communication, repair damaged tissue, and promote collagen production. This therapy works beautifully as a standalone treatment or combined with microneedling, PRF, or laser resurfacing to accelerate recovery and boost results. Exosome therapy is entirely biocompatible, making it an innovative, natural method for skin rejuvenation that harnesses the body’s regenerative capacity at a cellular level for smoother, firmer, and healthier-looking skin.
NAD+ IV Therapy
NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell of the body, playing a key role in energy production and DNA repair. IV infusion of NAD+ supports cellular regeneration, enhances mitochondrial function, and indirectly boosts collagen production by optimizing skin cell metabolism. Patients often notice improved skin tone, reduced signs of fatigue, and better overall vitality. While it is not injected directly into the skin, NAD+ therapy works from within to rejuvenate at a cellular level, making it a holistic, natural biostimulator option for overall anti-aging support.
Amino Acid Infusion Therapy
Collagen is built from amino acids such as proline, glycine, and lysine. Amino acid infusion therapy delivers these building blocks directly into the bloodstream via IV or injection, providing the skin with the essential nutrients it needs for repair and regeneration. This treatment supports fibroblast activity, enhances collagen and elastin synthesis, and improves overall skin health. By nourishing from within, amino acid therapy can complement other rejuvenation treatments, ensuring optimal collagen-building conditions. It’s a natural, biocompatible approach to supporting the skin’s structural integrity and maintaining a youthful appearance.
Collagen Induction Peptide Therapy
Peptides are short chains of amino acids that act as signaling molecules, telling skin cells to produce more collagen, elastin, and other structural proteins. Collagen induction peptide therapy delivers these naturally occurring compounds directly to the skin through topical application, microneedling, or injections. This helps repair damaged skin, improve firmness, and reduce the appearance of fine lines. Peptide-based treatments are gentle, safe, and suitable for most skin types, offering a natural boost to the skin’s renewal process while enhancing results when used alongside other biostimulator treatments.
Why Choose Royal Glow by Meditism?
Physician-Led Aesthetic Care
Results-Driven, Holistic Treatment Plans
Custom Solutions for Every Skin Type
At Royal Glow by Meditism, we combine medical expertise with innovative approaches and cutting-edge technology to deliver the highest level of results that are both safe and transformative. Every treatment is physician-led, ensuring the highest standard of care. We use only medical-grade treatments and tailor each plan to your unique skin type, condition, and goals—no cookie-cutter solutions. Our holistic, results-driven approach means we address not only the visible concern but also the underlying skin health, promoting lasting improvements. With a focus on minimal downtime, comfort, and natural-looking outcomes, we’ve built a reputation for excellence and trust, making us a premier destination for your unique aesthetics and cosmetics needs.
Benefits of Biostimulators
- Restore youthful volume naturally
- Improve skin firmness and elasticity
- Enhance hydration and radiance
- Reduce wrinkles and fine lines
- Long-lasting results with minimal downtime
Getting Started Is as easy as 1-2-3
Consultation & Skin Assessment

Consultation & Skin Assessment
Customized Injection Session

Customized Injection Session
Follow-up & Maintenance

Follow-up & Maintenance
Biostimulators Treatment
Which Type of Biostimulators Are Better — Natural or Synthetic?
Both natural and synthetic biostimulators have unique advantages, and the best choice depends on individual goals, preferences, and medical suitability. Natural biostimulators (like PRF, polynucleotides, and microneedling) use the body’s own biology to stimulate collagen production, offering high safety, minimal risk of allergic reactions, and gradual, subtle results. Synthetic biostimulators (like Sculptra® or Radiesse®) often deliver faster or longer-lasting effects with targeted volumizing capabilities. Many aesthetic experts recommend a combination approach — using natural treatments for overall skin health and synthetic options for structural correction — to achieve the most balanced, long-term rejuvenation results.
What Will I Look Like After?


What Will I Look Like After Biostimulator Procedure?
You may notice slight swelling or redness for a day or two. Some treatments offer instant results, while others work gradually over weeks.
Common Facial Concerns We Address with Fillers
Common Facial Concerns We Address with Biostimulators
How Long Does the Procedure Take?
Typically 30–60 minutes, depending on the number of areas treated.
Is the Procedure Painful?
Most patients describe it as mild discomfort. Numbing cream or local anesthetic is used to minimize any sensation.
Expected Result: How Soon Do I See Results?
Some results are immediate (e.g., Radiesse, Ellansé), while others develop over 4–12 weeks.
How Long Will Results Last?
Depending on the product, results can last from 12 months to 4 years.
How Frequent Can I Get Biostimulator Procedures?
Maintenance sessions are typically done every 12–24 months, depending on the product and your collagen response.
Are There Side Effects?
Common side effects include mild redness, swelling, or tenderness at the injection site. These resolve within a few days.
Why Clients LOVE Biostimulator Treatment
Nicole Daniella12 September 2025Trustindex verifies that the original source of the review is Google. I’ve been coming to Meditism Clinic for over a year now and every visit has been such a positive experience. The staff are always friendly and professional, and the quality of care is excellent. Dr. Marzieh is amazing—she’s done my filler and Botox multiple times and I honestly wouldn’t go to anyone else. She really listens to what you’re looking for, takes her time, and her technique is so precise. What I love most is how natural the results look—I always leave feeling refreshed and looking my best. She’s truly an expert at what she does! hodeis rezvanian5 September 2025Trustindex verifies that the original source of the review is Google. I’ve been seeing Dr. Shakourian Fard for some time now, and I’m very grateful to have him as my family doctor. He is kind, attentive, and always takes the time to listen and explain things clearly. His staff are also very supportive, welcoming, and helpful, which makes every visit a positive experience. I feel very comfortable and confident with his care, which is why I also decided to register my parents with him. We truly appreciate his professionalism and compassion, and I highly recommend him to anyone looking for a caring family doctor. mary sholeh16 August 2025Trustindex verifies that the original source of the review is Google. I’ve been a patient at Meditism Health and Wellness Clinic for some time, and I can say Dr. Shakourianfard and Dr. Langroodi and the whole team especially Ms. Sahar and Ms. Kimia are amazing. From the warm welcome at the front desk to the thoughtful care during appointments. Doctors listen carefully, explain everything clearly, and make you feel truly cared for. It’s rare to find a medical team that combines professionalism with such genuine kindness. I’m so grateful and highly recommend this clinic to anyone looking for excellent care. Fariba Vandehvar9 August 2025Trustindex verifies that the original source of the review is Google. Words cannot fully express how grateful I am to Dr. Hesam Shakourianfar. His profound knowledge, genuine care, and unwavering support have been a true light in my path. He is not only an outstanding doctor but also a remarkable human being who brings both science and heart into his practice. I feel truly blessed to have crossed paths with someone so inspiring, dedicated, and kind.Thank you, Dr. Shakourianfar and his wonderful team. Wilhilma Quinoneza6 August 2025Trustindex verifies that the original source of the review is Google. Since my family came in 2023, this clinic take care of us. Doctor Shakourianfard is our first family doctor. He is an amazing doctor, very knowledgeable and has heart for his patient. Thank u also to Dra. Mahsa Hassanzadeh Langroodi for taking care of me. She is a very beautiful doctor inside out. Also the staff are very accomodating and warm, especially Kim. My son, Ged, actually found this clinic and he made the best decision in choosing this place for our health concerns. Thank you Royal Glow by Meditism and to all the doctors and staff for taking care of me and my family. All the best and Bless... Aylar P31 July 2025Trustindex verifies that the original source of the review is Google. I’m very happy with Dr. Mahsa Langroody and her team, including Kimiya and Sahar. Dr. Mahsa always listens carefully and takes the time to understand my concerns. Everyone at the clinic is kind, helpful, and dedicated, and I always feel well cared for. Highly recommend! Nahal Farjad30 July 2025Trustindex verifies that the original source of the review is Google. I’ve been coming to Meditism Clinic for nearly a year now, and each visit has been consistently excellent. From the moment you walk in, the calm and welcoming atmosphere sets the tone for a positive experience. The front desk staff are friendly and organized, and Dr Hassan zadeh is exceptional — compassionate, attentive, and highly knowledgeable. Highly recommend this clinic to anyone looking for quality healthcare in a warm, professional environment.
Pre‑Procedure and Post‑Procedure Care
Pre‑Procedure
- Avoid alcohol and blood-thinning medications 24 hours before treatment
- Stay well-hydrated in the days leading up to your appointment
- Inform your doctor about all supplements and medications you are taking
- Avoid excessive sun exposure or tanning before the procedure
- Arrive with clean skin, free from makeup and skincare products
Post‑Procedure
- Avoid strenuous exercise or heavy sweating for 24 hours
- Keep the treated area clean and avoid makeup for the first day
- Follow your doctor’s personalized aftercare instructions
- Avoid direct sun exposure and use SPF daily
- Refrain from facials, massages, or other treatments on the area for at least 1–2 weeks
Frequently Asked Questions
Can I combine treatments?
Yes, Biostimulators can be combined with other procedures like fillers, Botox®, PRP, or laser treatments. Your provider will create a safe, customized plan to maximize results while ensuring the treatments complement each other and maintain natural-looking outcomes.
How much does Biostimulators cost?
Pricing varies depending on the treatment type, products used, and your personalized goals. Every plan is tailored to your needs, so costs are discussed during your consultation after a full assessment.
Can I go back to work the same day after Biostimulator Treatment?
Yes, most patients resume normal activities the same day. You may have mild redness or swelling, which usually resolves quickly. Your provider will give aftercare instructions to support healing and optimize results.
Will I look natural after my Biostimulator treatment?
Yes, Biostimulators stimulate your own collagen for gradual, subtle improvements. The goal is a refreshed, youthful look—never an overfilled or artificial appearance.
What kind of results should I realistically expect with my Biostimulator Treatment?
Expect gradual improvements in skin firmness, texture, and elasticity over several weeks. Results vary based on your skin type, chosen product, and overall treatment plan.
Who will be performing the Biostimulator treatment? Are they qualified?
All treatments are performed by licensed, medically trained professionals experienced in facial anatomy and advanced injection techniques to ensure safe, natural-looking results.
Can I combine this Biostimulator treatment with others?
Yes, combining Biostimulators with other treatments can enhance overall results. Your provider will recommend the best combination and timing for your specific needs.
Is this Biostimulator treatment permanent?
No, results are long-lasting but not permanent. Collagen stimulation benefits can last a year or more, with maintenance sessions recommended.
What happens if I stop my Biostimulator Treatments?
Your skin will return to its natural aging process. The collagen you’ve gained remains, but new production will gradually slow without ongoing treatments.
Are there any contraindications or people who shouldn’t get Biostimulator treatment?
Biostimulators aren’t suitable for those pregnant, breastfeeding, with active infections, severe allergies, or certain autoimmune conditions. Your provider will review your health history first.
How do I book a consultation or appointment for my Biostimulator evaluation?
Contact our clinic by phone, email, or online booking form. We’ll arrange a consultation to assess your skin, discuss your goals, and create a personalized plan.
What happens if I decide not to continue with Biostimulator treatments?
If you stop, your skin will age naturally. You won’t lose the improvements already achieved, but collagen production will slow over time without ongoing sessions.
🗓 Book Your Consultation Today
🗓 Book Your Consultation Today
📍 Conveniently located at Yonge & Sheppard – North York, Ontario
📞 Call: 416.222.1530
Surprise Bonus — Monthly Glow Giveaways!
Every month we pull one lucky client name to win an exclusive Royal Glow Biostimulator Treatment Credit (worth up to $300 toward Sculptra, Radiesse, PRF, or Collagen-Stimulating Microneedling).
